Typical dosing ranges for 20 of the most common peptides, and how to plug each one into the calculator to get exact syringe units. These ranges are commonly reported in research and community literature — they are not recommendations. Always follow the instructions of a licensed healthcare provider.
Retatrutide
GLP-1 / GIP / glucagon (metabolic)
Clinical trials
Typical vial
10 mg, 20 mg, or 30 mg
Common dosing range
2–12 mg weekly (titrated upward)
Frequency
Once weekly
Using the calculator: A 20 mg vial with 2 mL of water gives 0.1 mg per unit — 2 mg is 20 units, 12 mg is 120 units, which is more than a 100 U syringe holds. Use less water or split the draw; the calculator flags it.
Where this dosage comes from+
Retatrutide is an investigational triple agonist (GLP-1, GIP and glucagon receptors) from Eli Lilly. It is not approved anywhere yet.
In the phase 2 obesity trial (Jastreboff et al., NEJM 2023) people received 1, 4, 8 or 12 mg once weekly for 48 weeks. Higher doses started at 2 mg and stepped up every 4 weeks. The 12 mg group lost about 24% of body weight on average.
Phase 3 trials (the TRIUMPH program) are testing maintenance doses in the same 4–12 mg range. Gastrointestinal side effects rose with dose and were reduced by slower titration.
Semaglutide
GLP-1 (metabolic)
FDA-approved
Typical vial
2 mg, 5 mg, or 10 mg
Common dosing range
0.25–2.4 mg weekly (titrated upward)
Frequency
Once weekly
Using the calculator: A 5 mg vial with 1 mL gives 0.05 mg per unit — 0.25 mg is 5 units, 1 mg is 20 units. Re-enter the new target at each step of the schedule.
Where this dosage comes from+
Approved as Ozempic (type 2 diabetes, up to 2 mg weekly) and Wegovy (weight management, 2.4 mg weekly).
The Wegovy label starts at 0.25 mg weekly for 4 weeks, then 0.5, 1, 1.7 and finally 2.4 mg, each step lasting 4 weeks. The schedule is meant to limit nausea, not to build effect.
The 2.4 mg dose comes from the STEP trials, where it produced about 15% average weight loss over 68 weeks.
Tirzepatide
GLP-1 / GIP (metabolic)
FDA-approved
Typical vial
5 mg, 10 mg, or 15 mg
Common dosing range
2.5–15 mg weekly (titrated upward)
Frequency
Once weekly
Using the calculator: A 15 mg vial with 1 mL gives 0.15 mg per unit — 2.5 mg is about 17 units, 15 mg is 100 units and fills a whole 100 U syringe.
Where this dosage comes from+
Approved as Mounjaro (type 2 diabetes) and Zepbound (weight management and sleep apnea).
The label starts at 2.5 mg weekly for 4 weeks, then increases by 2.5 mg every 4 weeks as tolerated. Maintenance doses are 5, 10 or 15 mg.
Those maintenance doses are the three arms of the SURMOUNT-1 trial, where 15 mg gave about 21% average weight loss over 72 weeks.
Tesamorelin
GHRH analog
FDA-approved
Typical vial
1 mg or 2 mg
Common dosing range
1–2 mg per dose
Frequency
Once daily
Using the calculator: A 2 mg vial with 1 mL gives 0.02 mg (20 mcg) per unit — a 2 mg dose is the whole vial, 100 units.
Where this dosage comes from+
Approved as Egrifta to reduce excess belly fat in people with HIV-associated lipodystrophy.
The labeled dose is 2 mg injected under the skin once daily (newer formulations deliver an equivalent dose in a smaller volume). That dose came from the phase 3 trials that measured reduced visceral fat over 26 weeks.
Bremelanotide (PT-141)
Melanocortin (sexual health)
FDA-approved
Typical vial
10 mg
Common dosing range
1–2 mg per dose (label: 1.75 mg)
Frequency
As needed, max once in 24 hours
Using the calculator: A 10 mg vial with 2 mL gives 0.05 mg per unit — 1.75 mg is 35 units.
Where this dosage comes from+
Approved in 2019 as Vyleesi for low sexual desire in premenopausal women.
The label dose is 1.75 mg under the skin at least 45 minutes before activity, no more than once in 24 hours and no more than 8 doses a month. That dose was chosen in the RECONNECT phase 3 trials; nausea was the main side effect.
Sermorelin
GHRH analog
FDA-approved
Typical vial
2 mg, 5 mg, or 9 mg
Common dosing range
200–500 mcg per dose
Frequency
Once daily, usually at bedtime
Using the calculator: A 5 mg vial with 2.5 mL gives 20 mcg per unit — 300 mcg is 15 units.
Where this dosage comes from+
Was FDA-approved as Geref for growth hormone deficiency in children, dosed by weight at about 30 mcg/kg nightly. The branded product was discontinued in 2008 for supply reasons, not safety.
Today it is mostly prescribed through compounding pharmacies. Adult prescriptions are usually 200–500 mcg at bedtime, a dose taken from the pediatric label and clinical practice rather than large adult trials.
Thymosin Alpha-1
Immune
Approved outside the US
Typical vial
5 mg or 10 mg
Common dosing range
1.6 mg per dose
Frequency
Twice weekly
Using the calculator: A 5 mg vial with 1 mL gives 0.05 mg per unit — 1.6 mg is 32 units.
Where this dosage comes from+
Sold as Zadaxin (thymalfasin) in many countries outside the US for chronic hepatitis B and C and as an immune support alongside other treatments.
The 1.6 mg twice-weekly dose comes from that label and the hepatitis trials behind it, usually given for 6–12 months.
Semax
Nootropic
Approved outside the US
Typical vial
5 mg or 30 mg
Common dosing range
200–600 mcg per dose
Frequency
1–3 times daily, in courses
Using the calculator: A 5 mg vial with 2.5 mL gives 20 mcg per unit — 300 mcg is 15 units.
Where this dosage comes from+
Approved in Russia as nasal drops (0.1% and 1%) for stroke recovery and cognitive problems.
Prescribed doses there are given as drops in the nose, often in 10–14 day courses. Injected doses used elsewhere come from community practice, not trials.
Selank
Anxiolytic / nootropic
Approved outside the US
Typical vial
5 mg or 10 mg
Common dosing range
250–500 mcg per dose
Frequency
1–3 times daily, in courses
Using the calculator: A 5 mg vial with 2 mL gives 25 mcg per unit — 250 mcg is 10 units.
Where this dosage comes from+
Approved in Russia as 0.15% nasal drops for anxiety. Russian clinical studies used nasal dosing in 1–3 week courses.
Injected microgram doses are a community practice without trial support.
BPC-157
Recovery / repair
Research / community
Typical vial
5 mg or 10 mg
Common dosing range
250–500 mcg per dose
Frequency
1–2 times daily
Using the calculator: A 5 mg vial with 1 mL gives 50 mcg per unit — 250 mcg is 5 units, 500 mcg is 10 units.
Where this dosage comes from+
Not approved anywhere. Almost all data is from animal studies, typically about 10 mcg/kg in rats.
The 250–500 mcg human range is a community conversion of those animal doses. Only a few small human pilot reports exist, and the FDA has listed it as a substance compounders should not use.
TB-500 (Thymosin Beta-4)
Recovery / repair
Research / community
Typical vial
5 mg or 10 mg
Common dosing range
2–5 mg per dose
Frequency
1–2 times weekly
Using the calculator: A 10 mg vial with 1 mL gives 0.1 mg per unit — 2 mg is 20 units, 5 mg is 50 units.
Where this dosage comes from+
TB-500 is a synthetic fragment of thymosin beta-4. Full thymosin beta-4 was tested in human trials (as eye drops, skin gel, and IV for heart injury), but none led to approval.
The common pattern — a higher 'loading' phase for 4–6 weeks then lower maintenance — comes from veterinary and community use, not human trials.
Ipamorelin
Growth hormone secretagogue
Clinical trials
Typical vial
2 mg, 5 mg, or 10 mg
Common dosing range
200–300 mcg per dose
Frequency
1–3 times daily
Using the calculator: A 5 mg vial with 2 mL gives 25 mcg per unit — 200 mcg is 8 units, 300 mcg is 12 units.
Where this dosage comes from+
Reached phase 2 trials as an IV treatment for gut slowdown after surgery, but development stopped and it was never approved.
The 200–300 mcg injection range comes from clinic and community practice, based on doses that reliably raise growth hormone in early studies.
CJC-1295 (no DAC)
Growth hormone secretagogue
Research / community
Typical vial
2 mg or 5 mg
Common dosing range
100–300 mcg per dose
Frequency
1–3 times daily, often stacked with ipamorelin
Using the calculator: A 2 mg vial with 1 mL gives 20 mcg per unit — 100 mcg is 5 units.
Where this dosage comes from+
Also called modified GRF (1-29). It has no completed human trials of its own; dosing mirrors short-acting GHRH analogs like sermorelin.
Taken together with ipamorelin in the same syringe in community practice.
CJC-1295 (with DAC)
Growth hormone secretagogue
Clinical trials
Typical vial
2 mg or 5 mg
Common dosing range
1–2 mg per dose
Frequency
Once weekly
Using the calculator: A 2 mg vial with 1 mL gives 20 mcg per unit — 1 mg is 50 units.
Where this dosage comes from+
The long-acting version. Early human studies (Teichman et al., 2006) gave single doses of 30–60 mcg/kg and found growth hormone stayed raised for about a week.
Development stopped after a trial participant death (judged unrelated). The 1–2 mg weekly range is a community translation of those weight-based doses.
AOD-9604
Fat metabolism
Clinical trials
Typical vial
2 mg or 5 mg
Common dosing range
250–500 mcg per dose
Frequency
Once daily
Using the calculator: A 5 mg vial with 2 mL gives 25 mcg per unit — 300 mcg is 12 units.
Where this dosage comes from+
A fragment of growth hormone tested as an obesity drug. Phase 2b trials gave 1 mg daily by mouth for 24 weeks and did not show meaningful weight loss, so development stopped.
Injected microgram doses come from community practice, not from those trials.
GHK-Cu
Skin / repair
Research / community
Typical vial
50 mg or 100 mg
Common dosing range
1–2 mg per dose
Frequency
Once daily, in courses
Using the calculator: A 50 mg vial with 5 mL gives 0.1 mg per unit — 1 mg is 10 units, 2 mg is 20 units.
Where this dosage comes from+
A copper peptide found naturally in the body. Most human research is on creams and serums for skin, where it is a common cosmetic ingredient.
Injected doses have no clinical trial basis and come from community practice.
Melanotan II
Tanning
Research / community
Typical vial
10 mg
Common dosing range
250–500 mcg per dose (start low)
Frequency
Daily during loading, then weekly
Using the calculator: A 10 mg vial with 1 mL gives 100 mcg per unit — 250 mcg is just 2.5 units. Add more water for easier-to-read draws.
Where this dosage comes from+
Small University of Arizona studies in the 1990s used about 0.025 mg/kg under the skin. It was never approved; related drugs (afamelanotide, bremelanotide) were developed instead.
Regulators in several countries have warned against unlicensed products.
Kisspeptin-10
Hormonal / reproductive
Clinical trials
Typical vial
5 mg or 10 mg
Common dosing range
100–200 mcg per dose
Frequency
Varies; often a few times weekly
Using the calculator: A 5 mg vial with 2.5 mL gives 20 mcg per unit — 100 mcg is 5 units.
Where this dosage comes from+
Studied in university research on reproductive hormones and IVF egg maturation, mostly as IV infusions or single injections in controlled settings.
Not approved. Ongoing injection doses come from community practice.
MOTS-c
Metabolic / mitochondrial
Research / community
Typical vial
10 mg
Common dosing range
5–10 mg weekly, often split
Frequency
2–3 times weekly
Using the calculator: A 10 mg vial with 2 mL gives 0.05 mg per unit — 2.5 mg is 50 units.
Where this dosage comes from+
A peptide made by mitochondria. Evidence so far is almost entirely from mouse studies on exercise capacity and insulin sensitivity.
Human doses are community estimates with no trial support.
Epitalon
Longevity
Research / community
Typical vial
10 mg or 50 mg
Common dosing range
5–10 mg per dose
Frequency
Daily for 10–20 day courses
Using the calculator: A 10 mg vial with 1 mL gives 0.1 mg per unit — 5 mg is 50 units.
Where this dosage comes from+
Developed by Vladimir Khavinson's group in Russia. Their studies are small and largely not independently replicated.
The short-course pattern comes from those studies and community use; it is not approved anywhere.
Turn any regimen into syringe units
Whatever peptide and dose you're working with, the steps are the same: enter the vial contents, the water you added, your syringe size, and your target dose — the calculator shows the exact units to draw, the volume in mL, and the dose per single unit. The reverse tool works backwards from the dose per unit you want and tells you how much water to add.
Always verify these calculations with a qualified healthcare professional before relying on them.
This calculator is an educational and informational tool only. It performs arithmetic on the numbers you enter — it is not medical advice, and nothing here has been reviewed by a doctor or pharmacist.
Peptide compounds discussed in research contexts are not approved by the FDA for human use and are not evaluated for safety, purity, or dosing. Compounded or reconstituted solutions carry real risks: contamination, inaccurate concentration, and dosing errors.
Nothing on this site should be used to prepare, reconstitute, or administer any substance to yourself or anyone else. Always follow the prescription, product insert, and instructions of a licensed healthcare provider, and verify every calculation independently before acting on it.
Use of this tool is entirely at your own risk. No warranties are made as to the accuracy of any result, and its creators accept no liability for any outcome arising from its use.